Efficacy of bee pollen and beebread against Salmonella typhimurium in BALB/c mice

Abstract

The present work evaluate the antibacterial and antioxidant potential of bee pollen and beebread against the toxic changes induced by Salmonella typhimurium in BALB/c mice. The experiment was divided into six groups as; Gp1 was normal, Gp2 was infected with Salmonella enterica serovar Typhimurium at 2×104 CFU, Gp3 and Gp5 were administrated with bee pollen and beebread of Helianthus annus crop alone at 250mg kg-1 bw respectively; Gp4 and Gp6 were with S. typhimurium and bee pollen and beebread H. annus at 250mg kg-1 bw respectively. Different hematological and oxidative stress parameters were assessed in animals. It has been observed that Gp2 showed alteration in the level of all tested parameters as compared to the Gp1, which indicated the toxicity induced by bacteria, but after the treatment with bee pollen and beebread as in Gp4 and 6, their level ameliorated to near normal, which showed the effectiveness of the tested bee products against bacteria.