Ovicidal, larvicidal and pupicidal activity of Nelumbo nucifera Gaertn against the filarial vector Culex quinquefasciatus Say (Diptera: Culicidae)

Abstract

In the current investigation, different solvent leaf extracts of Nelumbo nucifera were tested for their mosquitocidal potential against the filarial vector Culex quinquefasciatus. Further, bioactive compounds of the crude leaf extracts of N. nucifera were identified using GC-MS analysis. The benzene leaf extracts of N. nucifera showed significant egg, larval and pupal mortality at concentrations of 62.5, 125, 250 and 500 ppm, respectively. Mortality of ovicidal, larvicidal and pupicidal effect at 500 ppm at 48 h period were 89, 38 and 67 per cent with LC50 values 4.247, 6.694 and 4.975 and LC90 values 5.881, 9.628, 6.565 ppm, respectively. GC-MS profile of the leaf showed seven peaks and the major components identified as nuciferine, steporphine and mecambroline (29.40%). The study confirms N. nucifera has significant mosquitocidal effects.